WEBVTT

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- Hey, we're going to get started. We'll reward those people that actually got here on time. My name's

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- Buff Brown, and I'm a member of BTOP. That stands for Bloomington Transportation Options for People.

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- We've had a livable cities speaker series going on now for about, we're on our sixth year, and today

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- we have our 18th speaker.

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- Our VTOP is an organization that promotes walking, biking, and transit and promoting those. We actually

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- work a lot with the city trying to encourage them to set policies that encourage those modes

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- of transportation. This is also sponsored by

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- A couple other groups, Health by Design is a group I want everybody to know about. It's how Gail and

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- I met, an organization out of Indianapolis that also promotes health by focusing on the form of the

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- city, urban form, and how that affects public health. And they're kind of, they're a local organization

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- in Indianapolis, but yet I think they have a statewide reach as well.

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- I hope that partners from all over Indiana join Health by Design and so they can collaborate. Also,

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- I'd like to introduce Hannah Laughlin to tell you a little bit about a local group called GOAL, which

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- stands for Get Onboard Active Living.

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- Our speaker today is going to touch a little bit on childhood obesity. So I just wanted those of you

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- who are in the audience who maybe don't know about our local efforts around childhood obesity to just

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- hear a little bit more about that before we start. So the goal program, as Buff said, stands for Get

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- On Board Active Living. And it's a free community-based childhood obesity program for not only children,

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- but also their parents. And it's made possible by seven local community partners who give in-kind donation

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- and staff time to be able to let us

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- including IU Health Bloomington, the City of Bloomington Parks and Recreation, the Monroe County YMCA,

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- Southern Indiana Pediatrics, MCCSE, RBB, and IU, both the Department of Kinesiology and the Office of

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- Community Health Engagement. So our program is for children from the ages of six to 18 who are overweight

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- or obese, and it's free, it's family-oriented, and it's community-focused. We try to get our kids out

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- in the community to use the resources

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- that we have here in Bloomington that can help them lose weight. And if anybody's interested in more

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- information, my program team is here. Raise your hands so they can help answer questions if you have

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- any at the end. Thank you. All right. Dr. Liu is a research scientist at the Children's Health Services

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- Research Program in Indianapolis. He is an associate professor of

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- clinical pediatrics at the IU School of Medicine. And so let me introduce Dr. Gil Lu. Thank you. Bye.

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- So it's a real pleasure to be here talking with you today. And if you want to interrupt at any time,

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- just do so. Yell out, hey, Gil, I have a question or a comment. I'd be delighted to make this a little bit more

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- of a dialogue than just me lecturing to you. And let me see if I can get this to go. Okay, so I just

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- wanted to start out by reviewing where the country stands in terms of rates of obesity. In actually

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- the late 80s, the US Centers for Disease Control and Prevention, the CDC, decided they wanted to do

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- nationwide surveillance of obesity rates and they thought a good way to do that was to get on the phone call

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- randomly dial people in a representative sample and ask them many questions, two of which are how tall

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- are you and how much do you weigh? So we know that there are biases in that type of question. If you're

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- a woman and somebody asks you how much do you weigh, what do you typically do? You under report. And

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- if you're a guy and somebody asks you how tall you are, what do guys typically do? They say that they're

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- a little bit taller than they might measure.

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- So anything that the CDC got they knew from the start that it was probably a very conservative and likely

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- modest estimate. The first kind of complete data across the nation rolled in in 1995 and the color scheme

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- is that if you are light blue then 5 to 10 percent or less of your adults had a BMI greater than 30.

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- Are all of you familiar with body mass index, how that's calculated? Okay, so just to review.

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- That's a way of adjusting your weight for your height, and it is a rough screen for whether you're carrying

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- excess fat tissue on your body. So we know some people like, you know, who's Sylvester Stallone is,

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- he's kind of built like a square, right? He's very, very muscular. He's kind of, you know, he's not

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- the tallest guy. He's got a big BMI, but clearly he doesn't have obesity or overweight. So BMI has its

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- limitations, but overall,

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- It's a pretty good estimate for whether you are normal weight, overweight, or underweight, 1995. And

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- this is the most current data from 2009. And you can see that essentially we've had to erase the blue

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- color scheme and completely revise and change how we're looking at the rates of overweight.

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- And in fact, most of the states in the US now have a rate of obesity greater than 30%, more than one

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- out of every three adults has a BMI greater than 30. And actually, the one lone blue state is no longer

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- blue. So Colorado used to have a rate of overweight that was less than 15%. But now, they join the rest

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- of the country in having at least one out of every four adults having a BMI greater than 30.

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- So my health times have changed. We've seen this literal epidemic and explosion in rates of obesity

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- across our country. And this is sort of that same data but showing you the trend over time. So this

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- is a line graph starting in the late 80s going up to, you know, close to current day. And there are

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- some things to notice about this. One is that for,

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- Overweight, which we define as a BMI between 25 and 30, that rate has stayed about the same. But we've

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- seen most of the increases in people with BMI greater than 30 and in BMI greater than 40, which we define

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- as morbidly obese and has very, very serious implications for health. So not only have we seen it happen

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- across the country, but the severity of the rates seems to be increasing as well.

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- So for kids, you can't very well call up a kid and ask them how tall they are and how much they weigh.

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- It's just oftentimes they won't give you anywhere near a precise report. So what have we done instead?

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- They've actually paid for vans to go out across the US and measure children and do other health data

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- collection. And this shows that data for childhood obesity

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- And in general, the message is that we've seen similar rapid rises in number of kids who are obese,

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- a very clear trend of rise over time. And the perhaps most worrisome thing about this is do you see

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- the orange line at the bottom? That not only are we seeing children become overweight, but toddlers

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- and preschoolers are also seeming to become overweight more quickly. So Hannah, you've got to get

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- programs for kids younger than six. Because if you wait that long, you're going to miss a very important

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- window. OK, a little bit of trivia. Anybody know who started the National School Lunch Program? What

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- president? Truman in 1946. And he said that it was important for schools to deliver lunches to safeguard

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- the health and well-being

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- of the nation's children, and also a measure of national security. So what had we been dealing with

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- immediately before 1946? A war across the world. And interestingly, back in the 40s, the issue was not

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- obesity, which is a concern for how well our soldiers are able to defend us now, but actually underweight,

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- and particularly from Midwestern.

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- recruits, they were showing up so malnourished that they were unfit to serve as soldiers for this country.

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- So that was one of the main reasons why we started the school lunch program. And it might have times

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- of change. It used to be that the witches had to worry about fattening the kids up first. But we live

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- in an entirely different world now. So why do we worry about a BMI of 30? How did we pick this number?

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- of 30 for body mass index. Well, it happens that we've been following people now long enough to where

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- we can statistically determine that if your BMI exceeds 30 as a population, you are at much higher risk

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- for terrible health outcomes. And I'll just highlight two of them for you, or a few. But one for adults

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- came out in this paper in the Lancet just last year. And they looked at a million adults across 57 studies,

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- a worldwide view.

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- If you look, this paragraph I'm going to blow up for you, but moderate obesity, a BMI of 30 to 35 was

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- associated with approximately three year loss of life compared to normal weight individuals. And if

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- your BMI is greater than 40 in that morbid obese category, then you lose 10 years of life. And that's

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- equivalent to smoking your whole life. So I don't know if, you know, how you feel about tobacco use

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- or weight, but to me,

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- the proposition of one-third of our population in this country looking potentially at a very significant

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- shortening of their lifespan is something's got to change, right? And this is secondary stuff but I'm

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- sure many of you have heard about the Affordable Health Care Act and the need to reform our health care

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- expenditures, how much of our

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- gross domestic product is using to support healthcare, clearly we know that in overweight individuals

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- compared to normal weight that we spend much more on their care. So 41% more, $1.4 to every one for

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- a normal weight individual. So it's also a heavy economic burden as well.

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- For children, we don't know as much about the consequences of early overweight as far as how that's

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- going to translate into lifelong health impact, but it's not a big stretch to say that it's probably

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- just going to accrue more and more morbidity and mortality. But interestingly, we have seen that at

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- younger and younger ages, we're seeing clinical conditions that used to be only associated with overweight

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- in adults showing up in our children.

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- So there is a study in the southern U.S. that looked at how many 5 to 10-year-olds who are overweight

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- have elevated blood pressure, elevated cholesterol, are beginning to become resistant to insulin and

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- have pre-diabetes. And half of those kids had one of these factors, a quarter had two or more. And that's

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- something that we just really have no idea how that's going to play out.

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- early and shocking and dangerous for kids to have. Findings like hypertension, hyperlipidemia, and insulin

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- resistance at pre-adolescent ages. And then when you ask about health risk behaviors, children who are

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- overweight report increased use of alcohol and tobacco, less exercise, lower school performance, more sadness,

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- and lower quality relationships with their peers. So there's not just this clinical finding but also

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- heavy psychosocial burden as well. So what might have changed over the past 30 years to lead to these

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- rapid rises in obesity?

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- Many people think that it's a combination of our genetic predisposition and a rapidly changing environment

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- that's causing us to become more and more overweight. So just a diagram that in the past, well we know

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- that you put fat on your body if your energy quotient Q exceeds your work quotient W. So just simply

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- if you're eating more calories then you're burning in a day.

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- Many people will convert that into fat tissue and just store it. That's how our genes were made. And

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- that served us very, very well in the past when we were hunter-gatherers. So food was scarce. We had

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- to work hard to get it. And we needed to store energy. And there's been hundreds and hundreds of years

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- of environmental pressure to make us very thrifty in terms of our calories. And the thinking is in the

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- past three decades,

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- our environment has radically changed to where now we have a very, very easy time of getting lots of

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- Q and we essentially have to do no W. So our world is such that we can consume calories very, very readily

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- without hardly any work to get those. And you see that before our genotype, which was lean,

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- and we had to conserve our energy is now showing up as the overweight phenotype, same genotype. So clearly

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- our genes haven't changed in 30 years. It's unlikely that across the whole population something's mutated

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- in our DNA, but much more likely that we're seeing the effects of a very different environment that's

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- changed just over the past 30 or 40 years. So these are just, again, some lighthearted slides, but the

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- biggest hamburger in the world is 11 pounds.

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- And several people have taken it on. Eric didn't finish it. Kate did, unbelievably. And then I think

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- one of the most worrisome things we see is how foods marketed to kids. So even though they call cereal

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- mud and bugs, you can't see it because it's like brighted out. Kids buy the stuff. They love it. They

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- demand it from their children. So there are all of these kind of dangerous social phenomenon going on.

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- And we really have compartmentalized physical activity in our lives. So even the gems, we see escalators

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- and people choosing the easier route to get there. And I love this timeline. It showed up in the Washington

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- Post. And it started on my birthday, 1970. How many of you here are younger than 30? I'm just curious.

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- Raise your hand. A large majority of you. And that's really cool. I'm really glad to be speaking to

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- a young audience.

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- In 1970, again, sorry that you can't see this, but the prevalence of child obesity was 4%, one-third

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- to one-quarter of what it was now. And since I was born, there's been all of these amazing changes like

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- HBO and the first VCR and personal computer. The Happy Meal came in at 1978, the 7-11 big gulp in the 80s.

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- in where are some other like really neat things. I was trying to find somewhere on here like more and

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- more women are working so more and more kids are having prepared food or less time eating together as

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- a family. By the start of the 2000s, potatoes and white iceberg lettuce made up half of the vegetables

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- that we eat. So we had a very, very narrowing of the diversity of our fruit and vegetable intake.

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- And then at the beginning of this decade, we had to have things like Husky car seats. And Cookie Monster

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- could only talk about cookies as a sometimes food. And then now, you know, we're really trying to backpedal

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- and make up for all of these things that, you know, we thought were great. And they are great in some

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- ways, but they're also affecting our health in a very adverse way.

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- People have said it very eloquently. I'll read the middle and the last one. The current US environment

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- is characterized by an essentially unlimited supply of convenient, inexpensive, palatable, energy-dense

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- foods coupled with a lifestyle requiring negligible amounts of physical activity for subsistence. That's

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- the world we live in today. And because of that, genes have loaded the gun. Hundreds of years have made

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- us very, very thrifty in terms of hanging on to our calories and environment has pulled the trigger.

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- And now we see one out of every three US adults overweight, one out of every five or six kids overweight,

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- and children as young as two to five becoming overweight. The other thing, and I'll talk a little bit

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- more, so diet is clearly a major piece of this. And I'm not going to talk as much about diet today.

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- I'm going to lean more towards physical activity because that's my research interest. So forgive me

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- for kind of setting aside

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- but I'm going to focus more on physical activity and what we can do to design communities to promote

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- physical activity. But if you look at what happens from late childhood to adolescence, physical activity

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- basically steeply declines. And while physical activity is steadily decreasing from early adolescence

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- to late adolescence, which is the x-axis of this chart,

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- And girls, this is hours per week on the Y axis. We're seeing more and more computer use. And interestingly,

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- TV is kind of leveled off in our generation. So we're still getting a lot of screen time, but it's moved

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- from television to other electronics. And the same for boys, except even more so. Our young men are

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- just really glued to some sort of electronic screen that is not TV.

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- So this is for Hannah and the goal team. What do we know about weight loss programs? It's a big challenge.

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- So if you really, really give people good counseling about aggressive lifestyle modifications, so really

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- increasing their physical activity, teaching them how to eat a nutritious diet, we know that pretty

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- reliably we can get people to lose 10 to 20% of their current body weight.

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- But what we don't know is how to help them keep that weight off. So 80% of people who have been enrolled

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- in good clinical trials of weight loss programs at the five-year mark have actually exceeded their starting

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- weight. So we can get weight off in the short term. About 20% of your weight is a good goal and proven

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- success in weight management programs. But very, very few programs know how to sustain weight loss.

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- At five years, virtually all of them fail.

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- And this is a complicated chart, but it's a way to represent a meta-analysis, which means to take all

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- of the literature that exists that is strong evidence and represent it on a page or several pages. And

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- this just shows the current state of child weight management programs. So the first thing I want to

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- point out is that you can fit all of the evidence on one page. That's kind of sad. So we've got a long

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- way to go to figure out how to help kids manage their weight.

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- And this line right here, if you touch this line, your trial is no different experimental group versus

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- control. So anything touching this line showed no significant effect. So you can see most of the studies

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- are touching the line. Only a few are showing statistically significant weight management and there

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- are one, two, three, four, five trials right now out of all of the published literature that shows that we can,

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- effectively get kids to lose weight in weight management programs. And they have very, very modest effects.

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- So in general, the kids drop between four and eight pounds in the program after six to 12 months. None

00:21:56.933 --> 00:22:04.158
- of them enroll kids that are preschool age. So that's a wide open frontier for research. And we don't

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- know whether it benefits like their lipid status or their blood pressure or their insulin sensitivity.

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- And there is some evidence for older kids that some of the weight loss medications work, but again not

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- for long term and actually many of these have bad side effects. So we have no idea once a child or a

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- person becomes overweight how to help them in the long term. That's kind of the overall summary of this.

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- So I'm really like giving you such depressing news. The world is becoming more and more overweight.

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- That overweight has horrible health consequences and once a person is overweight there's very little

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- return to normal weight for those people who have been enrolled in good trials that have collected data

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- in the long term. So what does that hold for us as far as priorities? I would suggest that instead of

00:22:55.408 --> 00:23:02.330
- focusing on treatment, while it's important and should receive continued research, especially for kids,

00:23:02.330 --> 00:23:09.384
- we need to look at prevention. Because it seems like treatment is not the answer, at least at the current

00:23:09.384 --> 00:23:10.782
- state of things. OK.

00:23:10.978 --> 00:23:17.849
- More trivial pursuit, which of these household appliances is least used by immigrant families in the

00:23:17.849 --> 00:23:25.128
- US? Anybody want to take a stab at it? It actually is the dishwasher. Anybody here grow up in an immigrant

00:23:25.128 --> 00:23:31.454
- family? I can't really tell people's race, ethnicity. I did, my parents moved here from the,

00:23:31.906 --> 00:23:37.444
- from China and Taiwan in the late 60s and they sure enough use their dishwasher as a drying rack. They

00:23:37.444 --> 00:23:42.981
- just don't believe it gets dishes as clean as they can and they think it's a total waste of like water

00:23:42.981 --> 00:23:48.465
- and electricity. Why do I ask you that? Well, the person who invented the front loading dishwasher is

00:23:48.465 --> 00:23:50.078
- from Indiana, his name is Sam

00:23:50.178 --> 00:23:56.307
- Regenstrief and any house that has a front loading dishwasher pays a little bit on Sam's patent. So

00:23:56.307 --> 00:24:02.681
- you can imagine the Regenstrief family has just accumulated a fair amount of wealth and he's done very,

00:24:02.681 --> 00:24:09.117
- very good things with that money. One is that he's given it to the Boys and Girls Clubs of America which

00:24:09.117 --> 00:24:15.246
- is a great youth community organization. But the other is that he established where I work which is

00:24:15.246 --> 00:24:19.230
- the Regenstrief Institute at Indiana University in Indianapolis.

00:24:19.458 --> 00:24:26.027
- And another thing that Sam had great foresight to do is he said, why don't we go ahead and start working

00:24:26.027 --> 00:24:32.407
- on electronic medical records at the Regan Street Institute. That's one of the things I want for this

00:24:32.407 --> 00:24:38.913
- place to be a leader in. So Indiana has one of the longest standing, largest electronic medical records

00:24:38.913 --> 00:24:44.606
- in the world, which I think is really, really cool because it's a great tool for research.

00:24:44.738 --> 00:24:52.051
- So we have data on over 6 million patients. They've generated almost, you know, 900 plus million observations

00:24:52.051 --> 00:24:59.097
- and it's widespread. It's the nation's only city-wide medical record and it's rapidly becoming state-wide

00:24:59.097 --> 00:25:05.812
- in terms of getting disparate hospital systems to share data and store it so that people can look at

00:25:05.812 --> 00:25:06.942
- it and study it.

00:25:09.186 --> 00:25:15.968
- So I want to show you some analyses that we've done. We went into the record and asked for all heights

00:25:15.968 --> 00:25:22.619
- and weights on kids from 4 to 16, from 96 to present. And then we looked at whether or not they were

00:25:22.619 --> 00:25:29.335
- seen for well child visits versus sick visits. And then we categorized them in terms of their weight.

00:25:29.335 --> 00:25:35.920
- So we take care of about 10,000 patients a year. Many of them come for multiple visits, but many of

00:25:35.920 --> 00:25:37.566
- them only come one time.

00:25:37.666 --> 00:25:46.192
- We have a mostly publicly insured population, so they're fairly transient. And this just shows you that

00:25:46.192 --> 00:25:54.554
- they're normally distributed. So it's half boy, half girl, mostly younger, which is when kids come to

00:25:54.554 --> 00:26:03.326
- the pediatrician more. But you can see that half of our population is African-American, and over half have

00:26:03.458 --> 00:26:10.199
- either Medicaid or Medicare. So it's a low income, high minority population living in Indianapolis,

00:26:10.199 --> 00:26:17.007
- basically who I'm talking about. So one of the limitations of this work is I don't have a lot to say

00:26:17.007 --> 00:26:24.152
- about wealthy, non-minority subjects at present. We're trying to get that data in so as the record grows,

00:26:24.152 --> 00:26:31.364
- we'll have more of that population. And just like the national data, we've seen our obesity rates steadily

00:26:31.364 --> 00:26:32.510
- climb over time.

00:26:33.538 --> 00:26:39.919
- And this is interesting to me. So one thing that you can see is that our Latino subjects have the highest

00:26:39.919 --> 00:26:46.118
- rates of overweight. They're the collection of bars in the middle and that they're becoming overweight

00:26:46.118 --> 00:26:52.559
- at much younger ages. So we know that, you know, toddlers and preschoolers are rapidly becoming overweight

00:26:52.559 --> 00:26:58.699
- and especially among Hispanics and especially among Hispanic males. They seem to be at really, really

00:26:58.699 --> 00:27:00.926
- high risk for developing overweight.

00:27:01.154 --> 00:27:08.932
- early and then staying overweight throughout their childhood. And that's just shown here. It's very,

00:27:08.932 --> 00:27:17.402
- very hard to see, but this is a model that's virtually invisible. Age is on the bottom and rate of overweight

00:27:17.402 --> 00:27:25.334
- is on the top. And this just shows numbers of kids becoming overweight by a certain age. And you can't

00:27:25.334 --> 00:27:30.878
- see it, but this is the Latino curve. It's earlier than everybody else.

00:27:31.266 --> 00:27:40.268
- So at age 4, we saw about 15 to 20% of our Latinos already crossing a BMI threshold that would define

00:27:40.268 --> 00:27:49.447
- them as obese. So that population in particular deserves some attention. So America's losing the battle

00:27:49.447 --> 00:27:57.566
- against obesity. Sustainable weight loss has not been demonstrated. In Indianapolis, we see

00:27:57.954 --> 00:28:04.811
- clear patterns by race, ethnicity, and sex. And based on these things, we probably need to start working

00:28:04.811 --> 00:28:11.472
- on obesity as early as we can, like even with pregnant mothers before the child pops out of the womb.

00:28:11.472 --> 00:28:18.394
- Any questions? You guys hanging in there? OK, I see a couple in the back. Why don't we take two questions

00:28:18.394 --> 00:28:20.222
- that I'm going to motor on.

00:29:07.394 --> 00:29:12.638
- I think that's a very good hypothesis. I don't know of any specific literature that talks about stay

00:29:12.638 --> 00:29:17.934
- at home moms versus working moms. I do know that there have been many studies that show the more that

00:29:17.934 --> 00:29:23.334
- children eat breakfast at home and dinner at home, the healthier their diet composition is and the less

00:29:23.334 --> 00:29:28.318
- risk they have for overweight. So I think that connects. And then there was one other question.

00:29:39.746 --> 00:29:47.557
- Very, very good question. So it turns out that African American females have the next highest risk.

00:29:47.557 --> 00:29:55.525
- So it actually goes Hispanic males, African American females, Hispanic females, and then the rest are

00:29:55.525 --> 00:30:03.493
- pretty close. And one piece of good news that I didn't mention is it looks like recently our rates of

00:30:03.493 --> 00:30:05.758
- overweight have leveled off.

00:30:07.138 --> 00:30:14.861
- You know, so cause for, you know, a little bit of celebration there. But for certain subgroups,

00:30:14.861 --> 00:30:23.308
- the Latinos, maybe it's still rapidly climbing. So that's a great question. Okay, this gets to my second

00:30:23.308 --> 00:30:32.158
- half of the talk. And so now in terms of prevention, there are many ways to go about that. Policy approaches.

00:30:33.058 --> 00:30:39.807
- But I'm going to focus on something called the built environment. And that just means anything that

00:30:39.807 --> 00:30:46.692
- man decides to install in their communities. And I'm really looking at kind of larger scale features.

00:30:46.692 --> 00:30:53.441
- So while it could be, you know, stairs and signs and buildings, we're going to talk about ways that

00:30:53.441 --> 00:31:00.798
- we decide how to allocate land use to residential versus commercial landscaping that we do in street design.

00:31:01.122 --> 00:31:08.461
- are the features of the built environment that I'm going to be talking more about. So it seems pretty

00:31:08.461 --> 00:31:15.655
- clear that if we look at how we do our transportation infrastructure, how we decide to allocate our

00:31:15.655 --> 00:31:22.922
- land use mix, and how densely we develop residential areas, those things have been proven to promote

00:31:22.922 --> 00:31:28.318
- walking and biking in adults. So if you take a street network that is more

00:31:28.770 --> 00:31:35.394
- a grid structure versus the cul-de-sacs and disconnected streets that we see in suburbs, then people

00:31:35.394 --> 00:31:41.952
- walk and bike more on a grid. Similarly, if you take residential commercial retail and you blend it

00:31:41.952 --> 00:31:48.511
- all together like you see in the middle of cities, so people living in apartments that are close to

00:31:48.511 --> 00:31:55.200
- stores and also close to where they work, adults walk and bike more. And then lastly, in places where

00:31:55.200 --> 00:31:57.758
- there are more and more adults living,

00:31:58.402 --> 00:32:07.033
- densely in an area, that is also promoting a physically active lifestyle. And that probably makes sense

00:32:07.033 --> 00:32:15.747
- to a lot of you. So we're looking for the best ways that we can modify the built environment to increase

00:32:15.747 --> 00:32:24.461
- physical activity, to enhance a person's nutrition in their diet, and to keep them from being sedentary.

00:32:24.461 --> 00:32:28.030
- And we don't know how to do that for kids.

00:32:28.226 --> 00:32:34.830
- quite yet. So how many of you grew up on a cul-de-sac or a separated street? Yeah, yeah, many of you

00:32:34.830 --> 00:32:41.629
- did. It's a great place for a kid to be, right? It's safe, it's away from traffic, the parents can more

00:32:41.629 --> 00:32:46.206
- easily supervise what's going on, maybe you knew your neighbors more.

00:32:46.946 --> 00:32:53.113
- But urban designers who are looking for smart designs for adults hate cul-de-sac. So you can see there's

00:32:53.113 --> 00:32:59.045
- this kind of battle already set up for what do we do in terms of good things for kids? What do we do

00:32:59.045 --> 00:33:05.094
- in terms of good things for adults when the two things are so separate and distinct? Hard to say. What

00:33:05.094 --> 00:33:10.498
- we do know is that the more that you get a kid outdoors, the more active they are, which is

00:33:10.498 --> 00:33:16.606
- a neat association. And that we need more research into this area is kind of the summary of this slide.

00:33:18.594 --> 00:33:24.928
- And I have a particular interest in greenness. So the way that we landscape cities with more and more

00:33:24.928 --> 00:33:31.387
- vegetation and seeing if that improves health. And that's based on lots of kind of interesting studies.

00:33:31.387 --> 00:33:37.659
- So let me just holly a couple for you. One was just looking at people who were hospitalized that had

00:33:37.659 --> 00:33:44.180
- the bed by the window or the bed that didn't have the view. And it turns out that the patients who could

00:33:44.180 --> 00:33:48.030
- look out onto a green setting requested pain medication less.

00:33:48.514 --> 00:33:54.158
- Their nurses thought that they recovered better and they actually had an earlier discharge from their

00:33:54.158 --> 00:33:59.746
- hospital. And that, you know, hard to say exactly what's going on there, but I thought, and it's one

00:33:59.746 --> 00:34:05.335
- of the earlier starts at looking at the effect of greenness on health. And now we're seeing more and

00:34:05.335 --> 00:34:11.255
- more in studies that communal green spaces build a lot of community cohesion and good social interactions.

00:34:11.255 --> 00:34:16.788
- So gardens and parks are great places for neighbors to get to know each other. And I wanted to look

00:34:16.788 --> 00:34:17.950
- at how these spaces,

00:34:18.306 --> 00:34:28.116
- can get kids to be more active and to have less obesity. So, like I said before, we took all the patients

00:34:28.116 --> 00:34:37.556
- in our county out of our medical record system and we started mapping them as a start to look at what

00:34:37.556 --> 00:34:46.718
- their environments were like. And on this map, the purple dots is color coded by race and green is

00:34:47.042 --> 00:34:54.726
- Caucasian, purple is African-American, so what would you say about Indianapolis? Very segregated, right?

00:34:54.726 --> 00:35:02.264
- It's like oil and water along north-south boundaries. So that's the first thing that's just like, wow,

00:35:02.264 --> 00:35:09.655
- I didn't realize that blacks and whites are living so separately in our city, and they probably have

00:35:09.655 --> 00:35:14.046
- very distinct environments as a result of that. Next, we...

00:35:14.690 --> 00:35:21.204
- Anybody a geography major in here? Or doing any geographic information, spatial analysis stuff? I'm

00:35:21.204 --> 00:35:27.718
- not one of those people, but there's a way where you can look at observations in space and look and

00:35:27.718 --> 00:35:34.557
- see whether they're clustered. So we just wanted to know are overweight children clustering in our city?

00:35:34.557 --> 00:35:41.202
- And it turns out that they are. And especially when you look separately by race, the African American

00:35:41.202 --> 00:35:43.742
- children who are overweight are living

00:35:43.842 --> 00:35:49.920
- near other overweight kids. So again, another piece of evidence that suggests there's some

00:35:49.920 --> 00:35:56.598
- sort of environmental factor going on that's affecting kids' weight. OK. So we decided, well, let's

00:35:56.598 --> 00:36:03.410
- actually see if we can get at the greenness question. So we looked at the kids who are staying in our

00:36:03.410 --> 00:36:10.089
- hospital system so we can measure their weights over time. So it's better to have longitudinal data

00:36:10.089 --> 00:36:11.358
- versus a snapshot.

00:36:11.618 --> 00:36:20.553
- Let's look at the effect of greenness and residential density on their change of weight and BMI. And

00:36:20.553 --> 00:36:29.488
- this just says both greenness and residential density and individual level factors affect a person's

00:36:29.488 --> 00:36:38.600
- weight and that these two factors probably interact in some way. So that's our conceptual model. Let's

00:36:38.600 --> 00:36:39.838
- get into kind

00:36:41.762 --> 00:36:47.510
- detail, but anyway, we also included the age of the child, their race, whether they're boys or girls,

00:36:47.510 --> 00:36:53.314
- their starting weight, so whether they were overweight or normal weight at the beginning of the study,

00:36:53.314 --> 00:36:59.006
- how they were insured, the income level of their neighborhood based on the census, so sometimes poor

00:36:59.006 --> 00:37:04.641
- kids live in wealthier neighborhoods, sometimes poor kids live in poor neighborhoods, and the year,

00:37:04.641 --> 00:37:07.966
- because we know that obesity rates are climbing over time.

00:37:10.178 --> 00:37:16.832
- So how did we get at greenness? Well, it turns out that all the time satellites are flying over the

00:37:16.832 --> 00:37:23.885
- US and one of the things that they're collecting is information on vegetation. And so they take a picture

00:37:23.885 --> 00:37:30.871
- of the surface and by looking at two spectrums of light, the visible spectrum and the infrared spectrum,

00:37:30.871 --> 00:37:36.926
- you can actually determine how much plant matter there is and whether it's healthy or not.

00:37:37.730 --> 00:37:46.149
- It's just really useful for us. And that's called the Normalized Difference Vegetation Index, NDVI.

00:37:46.149 --> 00:37:54.737
- So we've got greenness in hand. And the scale goes from minus one to plus one. So if you're less than

00:37:54.737 --> 00:38:03.156
- 0.1, you're in a pretty non-vegetated place. And if you're from a half to one, you're in very, very

00:38:03.156 --> 00:38:05.598
- lush surroundings, a park or

00:38:05.762 --> 00:38:13.902
- Here it'd be like rainforest kind of. And then the city in Indianapolis collects data on every parcel

00:38:13.902 --> 00:38:22.601
- because they want to know how to tax. So for every little piece of land with a structure on it, Indianapolis

00:38:22.601 --> 00:38:30.742
- and I'm sure Bloomington too knows whether it's residential, commercial, industrial and then they use

00:38:30.742 --> 00:38:34.014
- that to collect funding, public funding.

00:38:34.626 --> 00:38:43.862
- land use as well. And then we took patients' homes and drew circles on them and said, tell me what the

00:38:43.862 --> 00:38:53.187
- NDVI is in the circle and what kinds of land use there are in the circle. And it turns out that there's

00:38:53.187 --> 00:38:55.518
- a bunch of good variation

00:38:55.618 --> 00:39:02.987
- in greenness across our city. So there were some places like parking garage or the core of our city

00:39:02.987 --> 00:39:10.799
- or industrial complexes where the NDVI was very, very low and there were people living near those places.

00:39:10.799 --> 00:39:18.316
- And then there were places like parks or cemeteries where it was super green and similarly there were

00:39:18.316 --> 00:39:25.022
- plenty of families and everything in between. In this study we had roughly 4,000 subjects.

00:39:25.282 --> 00:39:34.270
- We saw the same pattern as our general clinic population, so mostly younger than 10 years, a high rate

00:39:34.270 --> 00:39:43.258
- of publicly insured, a high rate of obesity, and many of them were living in low income neighborhoods.

00:39:43.258 --> 00:39:52.158
- So the average income of the neighborhood that a child lived in was 37,000, just to give you an idea.

00:39:53.666 --> 00:40:00.903
- Basically what we saw is that the higher the NDVI, the lower the rate of weight gain over time. So for

00:40:00.903 --> 00:40:08.281
- these thousands of kids in the urban location of Indianapolis, greenness was protective against obesity.

00:40:08.281 --> 00:40:15.377
- Now it's hard for us to say exactly, you know, does greenness cause lower weight over time? In order

00:40:15.377 --> 00:40:18.750
- to do that, we'd have to conduct an experiment.

00:40:18.914 --> 00:40:26.250
- But this is pretty good preliminary evidence that landscaping may be an approach to get kids more active

00:40:26.250 --> 00:40:33.517
- and to protect them from gaining excess weight. So higher greenness was associated with either declines

00:40:33.517 --> 00:40:40.644
- or lower rates of change in BMI. Residential density was less important in this group than we've seen

00:40:40.644 --> 00:40:48.190
- for adults. And we also looked at things like the street networks and they weren't very important for kids.

00:40:48.514 --> 00:40:56.385
- So. And this is one of the largest studies of its kind. It has lots of racial representation of minority

00:40:56.385 --> 00:41:03.881
- groups, which is also rare. And I had the lecture of working with geographers and urban planners to

00:41:03.881 --> 00:41:11.377
- set up the study. So those are some of the strengths. Why might greenness be a good thing for kids?

00:41:11.377 --> 00:41:17.374
- Again, the more time kids spend outside, we know the more active that they are.

00:41:17.602 --> 00:41:24.086
- In cities, it turns out that the greener a neighborhood is, the more it seems like people are caring

00:41:24.086 --> 00:41:30.763
- for their neighborhood. So if you're putting in the time to landscape an area, then there's likely more

00:41:30.763 --> 00:41:37.247
- social investment in that neighborhood. And we've seen through other studies that greenness produces

00:41:37.247 --> 00:41:44.052
- beneficial effects in terms of reducing stress, people reporting higher quality mental health, and higher

00:41:44.052 --> 00:41:47.390
- self-esteem as well. So we're going forward to look

00:41:47.682 --> 00:41:54.492
- at this more, and let me tell you briefly about that. So I'm going to go by these real quick. The next

00:41:54.492 --> 00:42:01.302
- thing we want to do, so we have the measures from the clinical record, we have the observations of the

00:42:01.302 --> 00:42:08.111
- urban form, but what we didn't know is whether kids were using the greenness or not, right? So we have

00:42:08.111 --> 00:42:14.921
- these big kind of gaps in the study. So how are we going to figure that out? We are going to give kids

00:42:14.921 --> 00:42:16.574
- GPS enabled cell phones,

00:42:17.058 --> 00:42:23.622
- and strap these little pager-like devices on them called accelerometers which measure all of your activity

00:42:23.622 --> 00:42:30.248
- over time. And they hold charges for a month so you don't have to recharge them. So we're going to directly

00:42:30.248 --> 00:42:36.444
- observe where kids go, where they accrue physical activity, and then we're going to also ask them in

00:42:36.444 --> 00:42:42.701
- interviews, tell me about the exercise that you're getting over the week, how you're using the places

00:42:42.701 --> 00:42:45.278
- near your home. And with this technology,

00:42:45.570 --> 00:42:52.767
- This is an example of a path of a person wearing the cell phone over time. So time is from early in

00:42:52.767 --> 00:43:00.108
- the day to later in the day rising. And then you can see the places where they go. And if you connect

00:43:00.108 --> 00:43:07.305
- the path data with the accelerometer data, oh, this is a bunch of kids. And then you can see places

00:43:07.305 --> 00:43:14.142
- where activity is elevated, which would be the peaks on the map, and where it's low, which are

00:43:14.946 --> 00:43:22.572
- flat areas of the map. So hopefully we'll get more at the missing behavioral measures, which we can't

00:43:22.572 --> 00:43:30.123
- get just by like extracting things from the medical record. And forgive me, but I'm going to blow by

00:43:30.123 --> 00:43:37.824
- these. We're also working with the public schools in Indianapolis to improve their physical education.

00:43:37.824 --> 00:43:44.926
- That's how we're delivering the GPS units and accelerometers. So I'm just going to go by this.

00:43:45.762 --> 00:43:53.961
- Ultimately, the way that I would love for this research to be applied is by the policy makers who actually

00:43:53.961 --> 00:44:01.240
- are designing the neighborhoods and incentivizing development. So one great thing we're seeing

00:44:01.240 --> 00:44:09.209
- in Indianapolis is a rapid expansion of urban trails, which has had a lot of benefits. Raising property

00:44:09.209 --> 00:44:15.262
- values, bringing amenities to low-income neighborhoods versus the urban sprawl

00:44:15.522 --> 00:44:25.216
- that we've seen in many places. And a lot more urban gardens in our city. And we've got a lot of work

00:44:25.216 --> 00:44:35.100
- to do. So in Indianapolis, we have much less parks than similarly sized cities in the US. We have very,

00:44:35.100 --> 00:44:41.182
- very low rates of public transportation and walking and biking.

00:44:41.282 --> 00:44:48.314
- If you look at the public infrastructure, the built environment that we have to support physical activity,

00:44:48.314 --> 00:44:55.345
- especially in terms of sidewalks, very low. So many, many opportunities for intervening. And I'll conclude

00:44:55.345 --> 00:45:01.983
- by just saying, you know, this work was supported by the National Institutes of Health and had a lot

00:45:01.983 --> 00:45:08.686
- of great partnerships. Geography, School of Public and Environmental Affairs, the Polis Center, which

00:45:08.686 --> 00:45:10.526
- is an urban research group,

00:45:10.946 --> 00:45:22.955
- and the biostatisticians to run the analyses. So thank you very much. I'd love to hear questions or

00:45:22.955 --> 00:45:35.924
- talk more with you about your ideas for how to prevent obesity through communities. So that's it. Questions

00:45:35.924 --> 00:45:38.206
- anybody? Go ahead.

00:45:44.866 --> 00:45:55.980
- Yeah, we're just starting that right now. Okay, so the question was I think related to the last few

00:45:55.980 --> 00:46:07.649
- slides given that we have the path data and the direct measurement of physical activity have we included

00:46:07.649 --> 00:46:14.206
- greenness as a part of analyzing that data and we just got

00:46:14.338 --> 00:46:21.585
- those observations from the schools a few months ago. So we are. We're going to look at, you know, one

00:46:21.585 --> 00:46:28.620
- of the hard things is you have this path and the GPS device can update itself every five seconds is

00:46:28.620 --> 00:46:35.797
- what we've set it to. And then you have a minute by minute measure of their activity. So we're buried

00:46:35.797 --> 00:46:41.214
- in data. And we've got to boil it down to destinations versus the, you know,

00:46:41.858 --> 00:46:47.841
- commuting from destination to destination and then figuring out how important is it when you're moving

00:46:47.841 --> 00:46:53.823
- by car from one place to another or if you're in your house versus your friend's house. So we're still

00:46:53.823 --> 00:46:59.922
- struggling with how to take that path, boil it down into a variable and then look at greenness for that.

00:46:59.922 --> 00:47:05.730
- So we could take the greenness over the whole path but I think we should wait it by time spent in a

00:47:05.730 --> 00:47:09.854
- place and then even when you're spending time in a place what activity

00:47:09.954 --> 00:47:22.336
- you're doing. So there's still some steps we're taking to transform the data into something that we

00:47:22.336 --> 00:47:26.174
- can plug into a stats package.

00:47:37.410 --> 00:47:44.936
- Yeah, so I'm not 100% sure where the public transit. Yeah, thanks, thanks, thanks. The question was,

00:47:44.936 --> 00:47:52.387
- given that Indianapolis has either passed a new public transportation act, I actually think they're

00:47:52.387 --> 00:47:59.913
- still in the middle of passing it. How might improvements in public transit be relevant to this type

00:47:59.913 --> 00:48:05.502
- of research into preventing obesity? So I think that that's still unclear.

00:48:06.082 --> 00:48:12.361
- that we don't know about Indiana is just how to get people on the public transit. And I don't know if

00:48:12.361 --> 00:48:18.578
- that's a question of there's so little good public transit that people just discount it as an option

00:48:18.578 --> 00:48:24.734
- or if we had a bunch of buses running all the time if people would get on them and use them. What I

00:48:24.734 --> 00:48:31.013
- do know is that for our patients, low income families who are race, ethnicity, minorities, they don't

00:48:31.013 --> 00:48:31.998
- have access to,

00:48:33.218 --> 00:48:40.954
- public places for fiscal activity. So often parks are removed from their neighborhoods and places to

00:48:40.954 --> 00:48:48.691
- buy fresh fruit and vegetables are removed. So they need some way of getting from where they live to

00:48:48.691 --> 00:48:56.427
- an amenity for health. And most of them rely on public transportation. So I think that it would help

00:48:56.427 --> 00:49:01.406
- but I don't know of any studies I can cite that would tell that.

00:49:02.242 --> 00:49:11.473
- Charlotte, and they studied the people that stopped driving and started riding the transit. And I think

00:49:11.473 --> 00:49:20.881
- there was an average loss of about seven pounds. But it's a study that's substantial. And also the amount

00:49:20.881 --> 00:49:29.935
- of walking that occurs from transit, for transit riders, people have found that to be around 20 to 30

00:49:29.935 --> 00:49:31.710
- minutes of walking.

00:49:32.258 --> 00:49:37.278
- per day, which wouldn't otherwise have existed.

00:50:14.850 --> 00:50:22.257
- Yeah, yeah. So the question is in Bloomington it seems like you have plenty of options but people are

00:50:22.257 --> 00:50:29.519
- either unaware of them or even if they're unaware they might have other barriers to accessing them.

00:50:29.519 --> 00:50:36.926
- So I think there's a lot of great research going on right now in terms of social media and marketing.

00:50:37.442 --> 00:50:45.058
- to help people because clearly what we've seen although it's probably becoming less is one, people were

00:50:45.058 --> 00:50:52.675
- unaware of the problem of overweight. So at an individual level many people at BMI of 25 to 30 actually

00:50:52.675 --> 00:50:59.998
- don't think that they're carrying too much weight when we can show that over a lifetime that weight

00:50:59.998 --> 00:51:07.102
- will cause their health to decline. So that's one is just perception of weight status and being,

00:51:07.362 --> 00:51:13.634
- activated to change your lifestyle. The second question of if you want to change your lifestyle but

00:51:13.634 --> 00:51:20.095
- you don't know how to use the things in your environment is a big challenge. So I can say there's many

00:51:20.095 --> 00:51:26.053
- instances of healthcare providers telling people that they need to lose weight, exercise more,

00:51:26.053 --> 00:51:32.451
- and eat better, but they are completely unaware of all of the environmental barriers that people face

00:51:32.451 --> 00:51:34.270
- when they do that and that's

00:51:34.722 --> 00:51:42.395
- True for everybody but especially so for families that have low income or come from a different cultural

00:51:42.395 --> 00:51:50.434
- background than their provider. So I think that there needs to be like a multi-pronged approach to addressing

00:51:50.434 --> 00:51:57.742
- this and people will hold up as an example what we've done with tobacco. So physicians have learned

00:51:57.742 --> 00:52:00.446
- to counsel better about tobacco use.

00:52:00.546 --> 00:52:07.613
- The policies about taxing tobacco, the availability of tobacco, and then the perception of tobacco in

00:52:07.613 --> 00:52:15.026
- media has been changed. And we've actually seen tobacco use decline by a lot over time. It's been actually

00:52:15.026 --> 00:52:22.301
- a very successful public health intervention. For obesity, the hard thing is it's not just one behavior,

00:52:22.301 --> 00:52:29.022
- not whether you're lighting up a cigarette or not, but it's what you eat, how you move, and then

00:52:29.314 --> 00:52:35.983
- Not only how you move, but how you keep from sitting still. So sedentary activity is separate from physical

00:52:35.983 --> 00:52:42.158
- activity, and both of them have to be addressed. So I think the tough thing is telling people where

00:52:42.158 --> 00:52:48.333
- their markets are, where they can exercise, what they should do at home, how they parent, all those

00:52:48.333 --> 00:52:54.817
- things. Really, really complicated interplay of behavior that produces this health condition of carrying

00:52:54.817 --> 00:52:57.534
- too much weight. Yeah, maybe a couple more.

00:53:10.658 --> 00:53:18.823
- Yeah, so the question is what is there about best practices or evidence for preventing obesity in toddlers

00:53:18.823 --> 00:53:26.607
- and preschool kids or managing obesity? And I'll just say right now it's an open question with active

00:53:26.607 --> 00:53:34.314
- studies underway and everything that's been reported is preliminary. So there are piloting programs,

00:53:34.314 --> 00:53:40.190
- one just to show that we can safely talk about like reducing caloric intake.

00:53:40.290 --> 00:53:46.487
- for a toddler and helping toddlers choose better foods to eat. We really don't know how to do that.

00:53:46.487 --> 00:53:52.685
- We know more about, you know, in terms of activity, if you want a toddler to be active, then it has

00:53:52.685 --> 00:53:58.944
- to be things like play instead of exercise. And you're right about the mothers are just as important

00:53:58.944 --> 00:54:05.762
- or perhaps more important than the child. So for toddlers, certainly, they're a product of their environment.

00:54:05.762 --> 00:54:09.790
- They're making very few or essentially no independent decisions.

00:54:10.530 --> 00:54:19.722
- intervene on the guardians that are providing their care. I think that's part of the problem. I would

00:54:19.722 --> 00:54:29.095
- actually argue again for families that have low income and live in very distressed cities, even if they

00:54:29.095 --> 00:54:38.558
- know the right things to do, often they have a hard time achieving those things. So one thing I hear all

00:54:38.658 --> 00:54:45.211
- the time is, I really would love for my kid to be active. I would love to be outside. That's the way

00:54:45.211 --> 00:54:51.893
- I grew up. But where I live, they have to stay in the house. And that's just what I have to do to keep

00:54:51.893 --> 00:54:58.381
- them safe. So I don't know. I think it's also creating supportive environments that currently don't

00:54:58.381 --> 00:55:04.350
- exist, as well as educating and enabling families and individuals to change their behavior.

00:55:05.154 --> 00:55:09.118
- Okay, I'll take one more and then maybe I'll talk with you individually. So go ahead.

00:56:25.474 --> 00:56:29.822
- we can do this, we really could, we just have to decide that we...

00:57:04.866 --> 00:57:14.589
- I think that's a great closing comment. So again, thank you so much for taking time out of your day

00:57:14.589 --> 00:57:24.506
- to come and attend this talk and I'll stick around and if anybody has any other questions I'd love to

00:57:24.506 --> 00:57:27.326
- speak with you individually.
